Publications

AI-enabled clinical trial framework for end-to-end site recommendation and enrollment projection

Real-world treatment patterns and clinical outcomes among cholangiocarcinoma patients treated with futibatinib or pemigatinib

Authors: Mahipal A, Christensen D, Penney K, Tepsick JG, Lan Z, Zhao R

Real-world effectiveness of MET inhibitors versus immunotherapy ± chemotherapy in 1L for patients with MET exon 14 skipping mutations in non-small cell lung cancer

Authors: Pradhan P, George R, Saini KS, J S, Veinalde R, Berraondo MI, Nunes Filho PRS, Dutra C, Batra U, Pecci F, Ricciuti B, Rider J, Cantini L

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Biomarker-defined outcomes in metastatic clear cell renal cell carcinoma (mccRCC) receiving first-line (1L) immune checkpoint inhibitor-based therapy

Renal cell carcinoma

Authors: Shah KU, Rider J, Pindale R, Zugman M, Jaime-Casas S, Abreu De Goes V, Moradi A, Salgia N, Zang PD, Castro DV, Mercier B, Zhang G, Li Y, Dizman N, ...

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Association of mRNA COVID-19 vaccination near immune checkpoint inhibitor initiation with outcomes: A real-world analysis

Multiple tumor types

Authors: Jiang C, Rider J, Kontoyiannis PD, Pandiri VK, Sadeghi N, Beg S

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National perspectives on artificial intelligence use in cancer care: Confidence, adoption, and barriers

N/A

Authors: van Oort T, Colwell NA, Flora DB, Dicker AP, Fortune E, Bires J, Penberthy DR, Patt DA, Ajayi O, Chung C, Beg S, Parwani AV, Plotkin E

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Contemporary real-world patterns of precision medicine in metastatic NSCLC

Lung cancer

Authors: Gor J, Singh S, Aseem A, Kataria S, Naffakh N, Nguyen RH

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Developing a pan-cancer foundation model for digital patient representation and clinical prediction across real-world oncology data

Multiple tumor types

Authors: Parmar D, Ruchlin I, Thummagunti S, Gurha P, Yip SS

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A multi-agent AI system integrating real-world data and competitive intelligence to generate automated trial eligibility recommendations

N/A

Authors: Yip SS, Thummagunti S, Auth K, Patel P, Prior K, Zambon B, Dupont F, Tibbs C, Chawla J, Gurha P

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Systemic anticancer therapy in patients with de novo metastatic pancreatic adenocarcinoma: A real-world analysis

Pancreatic cancer

Authors: Bajaj P, Pradhan P, Wang Y, Karpes-Matusevich AR, Lan Z, Kent B, Gustafson WC, Graham J

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Clinical outcomes among patients with metastatic non-small cell lung cancer (mNSCLC) who received immune checkpoint inhibitors (ICI) in first (1L) and second line (2L)

Lung cancer

Authors: Wonsettler T, Fridman A, Karpes-Matusevich AR, Penney K, Hertler AA

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Artificial intelligence–enabled analysis of unstructured EHR data for identification of actionable HER2-low breast cancer phenotypes

Breast cancer

Authors: Patel A, Williford A, Ephraim A, Soto Pérez de Celis E, Hafez M, Brown TJ, Keswarpu P, Chandwani S, Rider J, Gurha P, Beg S, Joseph-Thomas J

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Real-world trends in the evolving use of first-line therapy in metastatic castration-sensitive prostate cancer patients (mCSPC) in the United States.

Prostate cancer

Authors: Aragon-Ching JB, Pierattini C, Karovic S, Dvergsten E

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PSA nadir–stratified outcomes of ARPI doublet and docetaxel triplet therapy in metastatic prostate cancer

Prostate cancer

Authors: Zugman M, Rider J, Pindale R, Shah KU, Moradi A, Jaime-Casas S, Zang PD, Salgia N, Abreu De Goes V, Sahu D, Ebrahimi H, Barragan-Carrillo R, Dizman ...

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A US-based, retrospective, observational study of biomarker testing patterns across lines of therapy in patients with metastatic colorectal cancer

Colorectal cancer

Authors: Kolhe R, Mukherjee V, Ng S, Beruti S, Quadri S, Liu K, Zagadailov E, Kamalakar R, Werner M, Sepulveda A

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Clinical and molecular predictors of response to Lu-177-PSMA-617 in metastatic castration-resistant prostate cancer

Prostate cancer

Authors: Pe Benito RA, Mohammed SKM, Nathasingh B, Jairam S, Gordon S, Kong E, Chandwani S

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Survival outcomes of cabazitaxel or subsequent androgen receptor pathway inhibitor (ARPI) in post-docetaxel/ARPI metastatic castration-resistant prostate cancer

Prostate cancer

Authors: Barata PC, Green L, Kim C, Hwang Y

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Prevalence and distinct biological programs of small cell lung cancer molecular subtypes revealed by real-world clinico-genomics database

Lung cancer

Authors: Luo Y, Wang L, Jahchan N, Ansell P, Zhao X, Zhao W

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Epidemiology of folate receptor alpha expression in ovarian cancer by age, race/ethnicity, and histotype in a real-world, US-based clinicogenomic database

Ovarian cancer

Authors: Arend RC, Hoskins KF, Guadamuz JS, Calip GS, Clarke MA, Choi YC, Zhang Q, Lastra RR, Strickland AL, Lynam SK

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Multi-modal real-world data uncovers predictors of clinical response to TOP1i and optimizes ADC strategies in colorectal cancer

Colorectal cancer

Authors: Tafazzol A, Cruz-González S, Shi X, Dezso Z, Kline DE, Chen J, Ansell PJ, Popovic R, Chen R, Samayoa J, Zhao X, Zhao W

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A deep learning-based multimodal integration framework for clinical outcome prediction

Lung cancer

Authors: Zhang B, Tian H, Bui T, Choi YC, Cai MH, Ansell P, Shrotre A, Chirieleison S, Kolahi K, Zhao X, Samayoa J, Zhao W

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Harmonizing logical observation identifiers names and codes (LOINC) codes and units in real-world oncology data: Method development and evaluation

N/A

Authors: Naliyatthaliyazchayil P, Stenerson T

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Clinical outcomes of patients with metastatic colorectal cancer treated with trifluridine-tipiracil + bevacizumab by performance status

Colorectal cancer

Authors: Nusrat M, Zhao R, He Y, Penney KL, Lan Z, Wang Y, Salimi T, Roby L, Andre T, Calleja E, Cann C

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Real-world study characterizing patient characteristics, treatments, and unmet need in IO-ineligible patients with metastatic triple-negative breast cancer

Breast cancer

Authors: Nguyen M, Shah R, Leclair B, Kariburyo-Yay F, Matusevich A, Mandora P

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Androgen-receptor pathway inhibitors triplet therapy (ARAAT): Real-world outcomes in metastatic hormone-sensitive prostate cancer

Prostate cancer

Authors: Morgans AK, Khan N, Ghadessi M, McKay R, Chen G, George DJ

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Trifluridine–tipiracil with and without bevacizumab in colorectal cancer

Colorectal cancer

Authors: Nusrat M, Zhao R, Khan N, Wang Y, Penney KL, Cann CG, Salimi T

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Emulating comparative oncology trials with real-world evidence studies (ENCORE): Process development and methodological considerations for oncology real-world data

Multiple tumor types

Authors: Weberpals J, Schneeweiss S, Kehl KL, Rivera DR, Mishra-Kalyani P, Lerro CC, Larkins E, Narayan P, Curley R, Hahn G, Anand P, Natanzon Y, Belli AJ, ...

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Real-world study of use patterns and clinical outcomes for patients with myelodysplastic syndrome initiating oral decitabine and cedazuridine or intravenous/subcutaneous hypomethylating agents

Myelodysplastic syndrome

Authors: Zeidan A, Zhao R, Tepsick JG, Lan Z, Salimi T

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Exploration of real-world outcomes in patients with previously treated HR+/HER2- and triple negative metastatic breast cancer

Breast cancer

Authors: Sadetsky N, Prince P, Latimer H, Advani P, Smith-Gaziani D, Kaufman PA, Natanzon Y, Taylor A, Nguyen L, Freemantle N

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Impact of real-world response to first-line immunotherapy and chemotherapy on subsequent treatment outcomes in patients with advanced or metastatic non-small cell lung cancer

Lung cancer

Authors: Malhotra J, Viswanathan S, Mhatre SK, Dhillon IK, Patel R, Yohn N, Kariburyo-Yay F, Li X, Ricciuti B

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Real-world treatment patterns, recurrence, and overall survival of patients with muscle-invasive bladder cancer undergoing radical cystectomy in U.S. oncology practice

Bladder cancer

Authors: Squires P, Coutinho F, Tepsick JG, Rogiers A, Ramamurthy C, Li H, Morgan TM

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Pathway-level molecular evolution and composite molecular genomic risk following Lu-177-PSMA-617 in metastatic castration-resistant prostate cancer

Prostate cancer

Authors: Pe Benito R, Mohammed SKM, Nathasingh B, Liao J, Khotskaya Y, Jairam S, Chandwani S

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Utilization of liquid biopsy in metastatic castrate resistant prostate cancer (mCRPC): patient characteristics, treatment selection, and mutational status

Prostate cancer

Authors: Hall MS, Penney KL, Liao J, Gordon S, Overstreet B, Rossi M, Rider JR

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Biomarker prevalence in US patients with gastric/gastroesophageal junction adenocarcinoma (GEA) from real-world data

Gastric cancer/Gastroesophageal junction cancer

Authors: Rudra-Ganguly N, Luo H, Zhao W, Ganesan S, Predoiu R, Leibman R, Walker G, Ansell P

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A multi-agent system for automated identification of competitive clinical trials in colorectal cancer

Colorectal cancer

Authors: Yip SSF, Chawla J, Rossi MR, Chandwani S, Gurha P

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Real-world clinical outcomes among metastatic colorectal cancer (mCRC) patients with liver metastases who received trifluridine/tipiracil (FTD/TPI) or FTD/TPI + bevacizumab (FTD/TPI+bev) combination therapy

Colorectal cancer

Authors: Kim RD, Christensen D, Penney KL, Khan N, Yeola S, Pandiri VK, Zhao R

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A United States-based real-world study on biomarker testing and rebiopsy rates among patients with non-small cell lung cancer across lines of therapy

Lung cancer

Authors: Aggarwal C, Ng S, Kamalakar R, Beruti S, Simmons A, Beasley MB

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Predictive modeling for survival outcomes in surgically resected pancreatic ductal adenocarcinoma: A comprehensive machine learning approach using real-world data

Pancreatic cancer

Authors: Ahmed KS, Issaka SM, Cher BAY, Marcinak CT, Zafar SN

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Predicting real-world overall survival in advanced melanoma using machine learning

Melanoma

Authors: Wang F, Hathi D, Chi L, Wu N, Nkhoma E, Harnett J, Salvati ME, Lewis K, Li Y

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Seizure related 6 homolog (SEZ6) expression pattern and prognostic impact in a real-world cohort of patients with small cell lung cancer

Lung cancer

Authors: Chiang AC, Wang L, Xu D, Luo A, Ansell PJ, Wang S

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Real-world prostate-specific antigen (PSA) response with darolutamide or abiraterone in metastatic hormone-sensitive prostate cancer (mHSPC) triplet therapy

Prostate cancer

Authors: Morgans AK, McKay RR, Khan N, Ghadessi M, Chen G, George DJ

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Real-world characteristics and outcomes of patients with third-line or later metastatic colorectal cancer: Magnetic-101 study results

Colorectal cancer

Authors: Goetze TO, Xu Q, Ng S, Mudumba R, Kamalakar R, Quadri S, Desai K, Fang H, Patel M, Neagu Aristide MR, Jin Z

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Real-world risk of recurrence and treatment outcomes with adjuvant endocrine therapy in patients with stage II-III HR+/HER2- early breast cancer

Breast cancer

Authors: O'Shaughnessy J, Tolaney SM, Yardley DA, Hart L, Razavi P, Fasching PA, Janni W, Schwartzberg L, Kim J, Akdere M, McDermott C, Khakwani A, Pathak P, ...

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Correlation analysis of invasive disease-free survival and overall survival in a real-world population of patients with HR+/HER2- early breast cancer

Breast cancer

Authors: Graff SL, Tolaney SM, Hart LL, Razavi P, Janni W, Schwartzberg LS, Danyliv A, Akdere M, Ferrusi I, Adhikary RR, O'Shaughnessy JA

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Real-world treatment and outcomes for EGFR WT advanced/metastatic non-squamous non-small cell lung cancer: pooled analysis from project LUMINATE-101

Lung cancer

Authors: Girard N, Xu Q, Camidge DR, Baijal S, Ng S, Kamalakar R, Ratajczak C, Alhasani H, Crawford S, Karve S, Lu S

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Characteristics of real-world NATALEE- and monarchE-eligible populations with HR+/HER2- early breast cancer: A United States electronic health records database analysis

Breast cancer

Authors: Tarantino P, Rugo HS, Curigliano G, O'Shaughnessy JA, Janni W, Jhaveri K, Mouabbi J, Brufsky A, Hamilton E, O'Regan R, Santarsiero L, Akdere M, Ye F, ...

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Real-world treatment patterns and survival in people with metastatic castration-resistant prostate cancer following metastatic hormone-sensitive disease between 2020 and 2023 in the United States

Prostate cancer

Authors: Raval AD, Chen G, Korn MJ, Bernthaler A, Constantinovici N, Freedland SJ

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Quantification of information gained by linking claims data to an electronic health record cohort of patients with metastatic breast cancer

Breast cancer

Authors: Geddes J, Katz J, Asiimwe A, Brookhart MA, Carroll C, Eldemir L, Mucaj V, Nolan K, Ntalla I, Nielson CM

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Real-world treatment patterns among advanced non-small cell lung cancer patients in the US

Lung cancer

Authors: Chen Y, Carlson A, Schommer J, Stenehjem D, Zhang D

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Real-world characteristics, treatment modifications, and outcomes for patients with acute myeloid leukemia (AML) receiving hypomethylating agents (HMA) + venetoclax (VEN) as first-line treatment (1L)

Acute Myeloid Leukemia

Authors: Zeidan A, Wang Y, Yu R, Matusevich A, Zhao R

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Real-world monotherapy and combination usage of mogamulizumab among patients with mycosis fungoides or Sézary syndrome in the United States

Mycosis fungoides and Sezary syndrome

Authors: Haverkos B, Chang C, Ristuccia R, DeGutis I, Chang Y, Friderici J, Rozati S

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Real-world EGFR testing and adjuvant treatment patterns among patients with resected early-stage non-small cell lung cancer (NSCLC) in the United States

Lung cancer

Authors: Kariburyo-Yay F, Liang Y, Simmons D, Miller V, Pye J, Ursino G

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Shifting treatment patterns in chromophobe renal cell carcinoma: A U.S. real-world data analysis

Renal cell carcinoma

Authors: Zugman M, Rider JR, Dizman N, Jaime-Casas S, Castro DV, Mercier B, Salgia NJ, Shah K, Abreu de Góes V, Barragan-Carrillo R, Sahu D, Mandora PV, Hsu ...

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Using AI methodology to stack and harmonize two U.S. EMR databases

Breast cancer

Authors: Pierzynski J, Elashoff M, Lynn A, Mathur R, Chandwani S, Katz JA, Sadetsky N, McMahon P

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Leveraging NSCLC foundation models to predict biomarker testing pattern

Lung cancer

Authors: Yip SS, Parmar D, Ruchlin I, Thummagunti S, Chandwani S, Gurha P

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Correlation of intermediate clinical endpoints (ICES) for overall survival (OS) in localized or locally advanced prostate cancer (LPC/LAPC): Analysis of individual real-world data (RWD)

Prostate cancer

Authors: Jahn B, Krabbe LM, Merseburger AS, Shore ND, De Solda F, Nair S, Price M, Sacchi E, Schaeffer M, Tang A, McCallion J, Lin X, McCarthy SA, Mundle SD, ...

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Developing an EHR-based multifeature machine learning model to identify lung cancer subtype

Lung cancer

Authors: Chandwani S, Priya V, Vaidya VP

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Challenges in analyzing real-world evidence: Analysis of androgen deprivation therapy use for prostate cancer in the REASSURE study

Prostate cancer

Authors: Tran B, Yeh N, Gayle A, Holmes E, Hu J, Damineni S, Kebede N, Shore N

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Real-world clinical characteristics, treatment patterns, and clinical outcomes in US patients with stage I-III resected NSCLC without known EGFR mutations: The RESECT study

Lung cancer

Authors: Gray JE, Salomonsen RJ, Diaz Perez I, Wang A, Cai L, Wetherill G, Xiao Y, Fielden C, Georgoulia N

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Overall survival in EGFR-mutant advanced NSCLC treated with first-line osimertinib: A cohort study integrating clinical and biomarker data in the United States

Lung cancer

Authors: Sabari JK, Yu HK, Mahadevia PJ, Liu Y, Demirdjian L, Chen YH, Wang X, Passaro A

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Computational modeling of comprehensive genomic profiling to predict chemotherapy benefit in advanced NSCLC

Lung cancer

Authors: Aggarwal C, Watson D, Nair P, Kumar A, Khandelwal S, Chauhan J, Khanna S, George S, Dey A, Patil M, Ganesh N, Purushottam R, Kulkarni S. G P, Lala ...

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Effect of IFNG expression levels on real-world survival outcomes in patients with metastatic non-small cell lung cancer receiving immunotherapy

Lung cancer

Authors: Altoe M, Papillon-Cavanagh S, Poi M, Yip S, Oakland T, Rossi MR

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Real-world treatment options for metastatic NSCLC patients following progression on chemo-immunotherapy

Lung cancer

Authors: Cortellini A, P B A, Saini KS, George R, Di Vincenzo C, Nunes P, Novikov V, Huang H, Batra U, Chico I, Ramkissoon S, Russano M, Pecci F, Tiseo M, ...

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Real-world evidence shows no survival advantage with contemporary first-line strategies in papillary renal cell carcinoma: A call for randomized trials

Renal cell carcinoma

Authors: Zugman M, Rider JR, Dizman N, Castro DV, Mercier B, Shah K, Ebrahimi H, Jaime-Casas S, Barragan-Carrillo R, Sahu D, Vikramsinh Mandora P, Hsu J, Yip ...

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Developing a digital twin framework for colorectal cancer outcome prediction and robust clinical trial simulation

Colorectal cancer

Authors: Ruchlin I, Altoe M, Monberg M, Oakland T, Rossi M, Agarwal V, Chawla J, Gurha P, Yip SSF

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STREAMLINE - Retrospective cohort study of FMS-like tyrosine kinase 3-mutated acute myeloid leukemia: Real-world treatment patterns and clinical outcomes of patients in first relapse or refractory diagnosis

Acute Myeloid Leukemia

Authors: Zeidan AM, Yu R, Wang Y, Lan Z, Grinblatt DL, Elsouda D, Spalding J, Block A, Touya M, Walker MS, Pandya BJ

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Patients with advanced non-small cell lung cancer harboring MET alterations: A descriptive cohort study

Lung cancer

Authors: Oksen D, Boutmy E, Wang Y, Stroh C, Johne A, Nisbett AR, Ryder A

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(PB2488) Chart review study on the real-world cytopenia management of patients with acute myeloid leukemia treated with venetoclax and hypomethylating agents

Acute Myeloid Leukemia

Authors: Zhao R, Wang Y, Dijkstra M, Wacheck V, Salimi T

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(PB2779) Chart review study on dose modifications of patients with myelodysplastic syndrome treated with hypomethylating agents

Myelodysplastic syndrome

Authors: Zhao R, Wang Y, Sano Y, Yeola S, Wachceck V, Salimi T

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Comparison of outcomes for patients (pts) with R/R chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL) previously treated with Bruton tyrosine kinase inhibitor (BTKi) and venetoclax from the TRANSCEND CLL 004 study versus a matched cohort of real-world (RW) pts

Chronic Lymphocytic Leukemia

Authors: Wierda WG, Wang L, Liu FF, Tuazon SA, Perna SK, Gu F, Gu T, Yue L, De Benedetti M, Fang L, Chen L, Shadman M

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Identification of predictive subphenotypes for clinical outcomes using real world data and machine learning

Lung cancer

Authors: Pan W, Hathi D, Xu Z, Zhang Q, Li Y, Wang F

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Treatment patterns and survival by race among men with metastatic castration-resistant prostate cancer (mCRPC) in the United States: A US electronic medical record database 2020-2023

Prostate cancer

Authors: Raval A, Chen G, Korn M, Freedland S

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Real-world treatment patterns and survival in men with metastatic castration-resistant prostate cancer (mCRPC) who previously progressed from metastatic hormone-sensitive prostate cancer (mHSPC) between 2020 to 2023 in the United States

Prostate cancer

Authors: Raval A, Chen G, Korn M, Bernthaler A, Constantinovici N, Freedland S

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Biomarker testing and patterns of treatment in NSCLC patients: An IASLC analysis of ASCO CancerLinQ Discovery data

Lung cancer

Authors: Behera M, Joseph G, Rupji M, Huang Z, Bunn B, Wynes MW, Switchenko J, Scagliotti GV, Tsao MS, Belani CP, Sequist LV, Ramalingam SS

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Practice patterns and outcomes of conventional versus split-dose cisplatin in neoadjuvant ddMVAC in bladder cancer

Bladder cancer

Authors: Callihan EB, Kuna EM, Eule CJ, Kessler ER, Flaig TW

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Survival outcomes among metastatic castration-resistant prostate cancer patients treated with androgen receptor pathway inhibitor and docetaxel

Prostate cancer

Authors: Hwang Y , Wheeling T , Hatfield M, Kim C

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Clinical use and outcomes of androgen-receptor pathway inhibitors triplet therapy for metastatic hormone-sensitive prostate cancer (ARAAT)

Prostate cancer

Authors: McKay R, Morgans A, Khan N, Constantinovici N, Chen G, Ghadessi M, Appukkuttan S, Jhaveri J, George D

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Survival impact of adjuvant chemotherapy regimens for small (T1mi/a/b), node-negative (pN0), triple-negative breast cancer (TNBC)

Breast cancer

Authors: Johnson K, Kim J, Slover B, House A, Hoeting B, Sandoval B, Thakur P, Johnson R, Roy A, Quiroga D, Bader G, Davenport A, Williams N, Cherian M, ...

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Real-world side effects of targeted therapies: High-throughput association studies leveraging the CancerLinq Discovery lung cancer database

Lung cancer

Authors: Vento J, Bastarache L, Chen Q, Osterman T

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Leveraging real-world data sources for clinical oncology research: A review of studies published in ASCO publications

N/A

Authors: Lucido T, Greenberg M, Kania B, Karam J, Bates B

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Analysis of ASCO clinical guidelines authorship and institutional representation using HemOnc.org

N/A

Authors: Jain S, Mohsin A, Herzog C, Mishra S, Cowan A, Schoen M, Yang P, Warner J

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Adjusted comparison of amivantamab in combination with carboplatin plus pemetrexed from the PAPILLON study versus US real-world frontline treatments in patients with advanced NSCLC harboring EGFR exon 20 insertions

Lung cancer

Authors: Schaeffer M, Lin X, Ngo N, Perualila NJ, Caparros EQ, Hales FG, Hultén A

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HSD64 Real-world adjuvant nivolumab utilization in surgically treated muscle-invasive bladder cancer patients within U.S. community oncology practice

Bladder cancer

Authors: Squires P, Coutinho F, Tepsick JG, Stuart J, Ramamurthy C, Li H, Morgan TM

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Recurrence and its association with overall survival (OS) in muscle-invasive bladder cancer (MIBC) patients undergoing radical cystectomy (RC): A real-world analysis

Bladder cancer

Authors: Squires P , Tepsick J , Coutinho F , Rogiers A, Ramamurthy C , Li H , Morgan T

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Post-metastasis survival of patients with high-risk localized and locally advanced prostate cancer undergoing primary treatment in the United States: A retrospective study

Prostate cancer

Authors: Freedland SJ, Fernandes L, De Solda F, Buyukkaramikli N, Mundle SD, McCarthy SA, Labson D, Yang L, Pan F, Mir C

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Prognostic score models for acquired resistance to frontline anti-programmed cell death protein 1/programmed death-ligand 1 therapy in metastatic non-small-cell lung cancer

Lung cancer

Authors: Murray JC, Huang Q, Chen YC, Hu C, DiSantostefano RL, Wong C, Glatz L, Curran E, Villaruz LC, Hasan AN, Schoenfeld AJ

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Oncology trial emulation using real-world electronic health record data: Results of the Coalition to Advance Real-World Evidence through Randomized Controlled Trial Emulation (CARE) initiative

Multiple tumor types

Authors: Levy N, Sheridan P, Campbell U, Lenis D, O'Doherty I, Estrin A, Gautam N, Zhen T, Belli A, Carrigan G, Chan A, Chen J, Chia V, Dhopeshwarkar N, ...

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Real-world frontline treatments in patients with advanced non-small-cell lung cancer harboring epidermal growth factor receptor exon 20 insertions and adjusted comparisons versus amivantamab plus chemotherapy from the PAPILLON study

Lung cancer

Authors: Chouaid C, Bosquet L, Knott C, Li Z, Schaeffer M, Lin X, Schioppa CA, Perualila NJ, Diels J, Caparros EQ, Galea F, Hultén A, Greystoke A

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Goserelin 3-month depot shows non-inferiority to the monthly formulation in U.S. patients with premenopausal breast cancer: A real-world evidence study

Breast cancer

Authors: McCann KE, Osman N, Cannon J, Brent L, Wang Y, Tepsick J, Mandora PV, Miller V, Martin N, Kaklamani VG

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Epidemiology of MET gene mRNA expression in metastatic colorectal cancer: Analyses of a real-world clinicogenomic database

Colorectal cancer

Authors: Calip GS, Choi YC, Cai MH, McNeill AM, Ng S, Xu Q, Vasilopoulos A, Wu S, Zhao W

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Epidemiology of MET gene mRNA expression in metastatic colorectal cancer: Analyses of a real-world clinicogenomic database

Colorectal cancer

Authors: Calip G, Choi YC, Cai M, McNeill A, Ng S, Xu Q, Vasilopoulos A, Wu S, Zhao W

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Identifying cancer germline variants associated with patient prognosis and response by applying clinico-genomics data

Multiple tumor types

Authors: Wu S, Tsui M, McLaughlin RT, Dehal H, O'Donoghue CM, Qian J, Zhao K, Gillis BR, Rahimov F, Samayoa J, Zhao X, Zhao W

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Investigating clinical features and molecular mechanisms of long-term response and acquired resistance to immunotherapy in non-small cell lung cancer by applying real-world-data

Lung cancer

Authors: Wu S, Zhao W, Zhang B, Choi C, Akhand SS, Zhang Q, Chen J, Ansell P, Chen R, Zhao X, Samayoa J

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Pediatric cancer in the United States: A comparison of three data sources

Pediatric cancers

Authors: Pace N, Huang T, Chen Q, Liu Y, Choi YC, McNeill A

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The value of integrating urology and oncology real-world data for understanding prostate cancer management

Prostate cancer

Authors: Pe Benito R, Nathasingh B, Ray H III, Chandwani S, Morgan T

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Real-world use of accelerated approval oncology drugs subsequently withdrawn in the United States

Multiple tumor types

Authors: Coutinho F, Karpes-Matusevich A, Miller V

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Comparing traditional NLP methods and LLM-based extraction for identifying biomarkers in lung cancer

Lung cancer

Authors: Joseph-Thomas J, Keswarpu P, Singh N, Jiwani K, A B, Gurha P, Tiwari S, Yadav A, Samal V, Agarwal V, Lawrence M, Martin R

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Electronic health records (EHR)-based machine learning (ML) approach to predict risk of progression to metastatic melanoma after initial diagnosis

Melanoma

Authors: Pindale R, Gemmler K, Pisano S, Tarhini A, Rider J

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Machine learning model to forecast patient availability for oncology clinical trials

N/A

Authors: Kulkarni R, Vaidya V, Parmar D, Tibrewal A, Keswarpu P, Parikh R

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Training and validation of CARAai™: A multi LLM platform and data model to address oncology-specific challenges in clinical data extraction

N/A

Authors: Rider J, Vaidya VP, Jiwani K, Elton J, Culot L, Gurha P

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Estimating US cancer prevalence with community oncology EHR-based datasets via national benchmarks from SEER and NPCR

N/A

Authors: Ray H, Li J, Chandwani S, D'Ambrosio C

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Behavior of test specificity under an imperfect gold standard: Findings from a simulation study and analysis of real-world oncology data

N/A

Authors: Walker MS, Slipski L, Natanzon Y

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Real-world clinical outcomes of patients with metastatic colorectal cancer (mCRC) treated with trifluridine-tipiracil + bevacizumab by performance status

Colorectal cancer

Authors: Nusrat M, Zhao R, Penney K, Lan Z, Wang Y, Cann C, Salimi T

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Real-world patient characteristics and treatment patterns among cholangiocarcinoma patients treated with FGFR inhibitors

Cholangiocarcinoma

Authors: Mahipal A, Zhao R, Tepsick J, Lan Z, Penney K, Salimi T

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Real-world clinical outcomes of trifluridine-tipiracil monotherapy (FTD-TPI) and FTD-TPI + bevacizumab combination therapy (FTD-TPI+bev) in 639 black patients (pts) with metastatic colorectal cancer (mCRC)

Colorectal cancer

Authors: Nusrat M, Zhao R, Khan N, Wang Y, Pierre-Victor D, Tepsick J, R S, Cann C, Salimi T

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Real-world clinical outcomes of patients (pts) with metastatic colorectal cancer (mCRC) who received trifluridine-tipiracil (FTD-TPI) monotherapy or FTD-TPI + bevacizumab (FTD-TPI+bev) combination therapy

Colorectal cancer

Authors: Nusrat M, Zhao R, Khan N, Wang Y, Pierre-Victor D, Tepsick J, R S, Cann C, Salimi T

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Real-world effectiveness of frontline treatments among patients with chronic lymphocytic leukemia: Results from ConcertAI

Chronic Lymphocytic Leukemia

Authors: Roeker LE, Burke JM, Rhodes JM, Emechebe N, Jawaid D, Manzoor BS, Jensen CE, Ryland L, Liu Y, Marx SE, Sinai W, Roser J, Shadman M

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Biomarkers of response in patients with gastric/gastroesophageal junction adenocarcinoma (GEA) treated with telisotuzumab adizutecan

Gastric cancer/Gastroesophageal junction cancer

Authors: Strickler J, Raimbourg J, Ghiringhelli F, Cohen J, Kitagawa C, Sharma M, Lee KH, O'Neil B, Rudra-Ganguly N, Luo X, Roberts-Rapp L, Predoiu R, Zhao W, ...

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Folate receptor alpha (FRα; FOLR1) expression and persistence in ovarian cancer in clinical trial samples and real-world patient cohort

Ovarian cancer

Authors: Swisher E, Zhang Q, Mehibel M, Masica D, Lakshmikanthan S, Deutschman E, Ansell P, Coleman R

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Real-world evidence provides clinical insights into tissue-agnostic therapeutic approvals

Multiple tumor types

Authors: Sledge GW Jr, Yoshino T, Xiu J, Helmstetter A, Ribeiro JR, Klimov S, Gilg B, Gao JJ, Elton J, Oberley MJ, Radovich M, Abraham J, Spetzler D

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Patterns of concurrent chemotherapy selection in US patients undergoing trimodality therapy for muscle-invasive bladder cancer

Bladder cancer

Authors: Callihan E, Kuna EM, Robin TP, Eule CJ, Kim SP, Flaig TW

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Real world evidence comparison of first-line (1L) immune-oncology(IO)/tyrosine kinase inhibitor (TKI) vs. IO/IO combination therapy in renal cell carcinoma (RCC)

Renal cell carcinoma

Authors: Bolan P, Hui G, Low Y, Gombar S, Fan AC, Parikh DA, Shah S, Srinivas S, Khaki AR

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Survival outcomes of apalutamide as a starting treatment: Impact in real-world patients with metastatic hormone sensitive prostate cancer (OASIS)

Prostate cancer

Authors: Maughan BL, Liu Y, Mundle S, Wang X, Nematian-Samani M, Karsh LI

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Real-world (RW) frontline (1L) treatments (Txs) in patients (Pts) with advanced non-small-cell lung cancer (NSCLC) harboring epidermal growth factor receptor (EFGR) exon 20 insertions (exon20ins) and adjusted comparisons versus PAPILLON study

Lung cancer

Authors: Chouaid C, Bosquet L, Knott C, Li Z, Schaeffer M, Lin X, Schioppa C, Perualila N, Diels J, Quintero E, Galea F, Hulten A, Greystoke A

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Management of severe immune-related adverse events and outcomes in patients with advanced non-small cell lung cancer receiving immune checkpoint inhibitors

Lung cancer

Authors: Naidoo J, Johnson DB, Doran C, Wang Y, Zhang Y, Le TK, Hopson S, Dreyfus B, Lal LS, Vyas C, Goldstein S, Izadi Z

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Racial disparities in clinical trial enrollment among patients diagnosed with prostate cancer: A population-based cohort of oncology practices

Prostate cancer

Authors: Wiesen BM, Flaig TW, Gershman B, Konety B, Warren A, Kuna EM, Robin T, Kessler ER, Eule CJ, Breyer BN, Achua J, Kim SP

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Clinical characteristics and treatment of patients with small cell prostate cancer: Analysis of a real-world cohort from an oncology database

Prostate cancer

Authors: Eule CJ, Warren A, Molina Kuna E, Robin TP, Gershman B, Kim SP, Flaig TW

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Disparities in second breast cancer events and survival persist despite optimal treatment in hormone-receptor positive breast cancer: Analysis of the real-world ASCO CancerLinQ dataset

Breast cancer

Authors: Kantor O, Jones A, Mayer EL, Chavez-MacGregor M, King TA, Mittendorf EA

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Social determinants of health (SDOH) and Z code utilization among patients with breast cancer (BC)

Breast cancer

Authors: Jones N, Blair A, Lipschultz E, Koskimaki J, Smither B, Miller R

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Real-world outcomes comparing 3-monthly with monthly goserelin implant in premenopausal women with breast cancer

Breast cancer

Authors: McCann KE, Osman N, Cannon J, Brent L, Wang Y, Pierre-Victor D, Tepsick J, Mandora PV, Miller V, Martin N, Kaklamani VG

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Evaluation of treatment strategies for patients with stage IIIA non-small cell lung cancer in the immunotherapy era

Lung cancer

Authors: Alabaster A, Velotta JB, Tupper HI, Walker MS, Natanzon Y

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Real-world treatment and clinical outcomes in patients with metastatic castration-resistant prostate cancer treated with olaparib in the United States

Prostate cancer

Authors: George DJ, Kariburyo-Yay F, Aggarwal H, Tepsick J, Yu R, Li W, Orji C, Ghate SR

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Real-world use patterns and clinical outcomes for myelodysplastic syndrome patients initiating oral decitabine and cedazuridine or intravenous/subcutaneous hypomethylating agents

Myelodysplastic syndrome

Authors: Zeidan AM, Zhao R, Pierre-Victor D, Wang Y, Tepsick J, Lan Z, Salimi T

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Real-world treatment patterns in patients with mycosis fungoides or Sezary syndrome treated with mogamulizumab in the United States: A retrospective database analysis

Mycosis fungoides and Sezary syndrome

Authors: Haverkos BM, Chang C, Ristuccia R, Chang Y, Friderici J, Rozati S

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Mutations in the Bruton tyrosine kinase (BTK) gene in patients with chronic lymphocytic leukemia (CLL) receiving BTK inhibitors (BTKis)

Chronic Lymphocytic Leukemia

Authors: Skarbnik AP, Danilov AV, Hoffmann M, Awan FT, Scarpa F, Davies C, Oakland T, Kovach M, Lilyquist J, Munugalavadla V, Yong ASM, Shetty V, Allan JN, ...

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Real-world outcomes following ibrutinib dose reduction in patients with chronic lymphocytic leukemia/small lymphocytic lymphoma

Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

Authors: Shadman M, Salkar M, Srivastava B, Karve S, Emond B, Gogna P, Manceur AM, Lafeuille MH, Rava A, Sun H, Howarth A, Tomicki S, Agatep B, Jones B, ...

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Real-world comparative effectiveness in advanced NSCLC and high PD-L1 with 1L immune checkpoint inhibitors ± chemotherapy

Lung cancer

Authors: Hsu ML, Xia Q, Aggarwal S, Nkhoma E, R D, Hager T, Quek R, Feliciano J

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Real-world clinical outcomes among patients with non-squamous advanced non-small cell lung cancer (aNSCLC) treated with docetaxel-based regimens post initial standard of care (SOC) in the United States

Lung cancer

Authors: Shah R , Kariburyo-Yay F, Apple J, Lal LS , Miller V, Reuss JE

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Characteristics of real-world (RW) NATALEE and monarchE eligible populations: A US electronic health records (EHR) database analysis

Breast cancer

Authors: Tarantino P, Rugo HS, Curigliano G, O'Shaughnessy J, Janni W, Jhaveri K, Mouabbi JA, Brufsky AM, Hamilton EP, Oregan R, Santarsiero EC, Sum E, ...

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METPRO: Evaluating prognostic value of c-Met protein overexpression and concurrent biomarker presence

Lung cancer

Authors: Le X, Aggarwal C, Simmons A, Crawford SA, Ng S, Chen C, Karve S, Stein S, Woll K, Ansell PJ, Mistry A, Bryant D, Wistuba II

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Real-world second-line outcomes of NSCLC patients receiving first-line chemotherapy plus immunotherapy

Lung cancer

Authors: Russano M, Cantini L, P B A, George R, Nunes P, Tolba K, Dutra C, Chico I, Cortellini A, Pecci F, Alessi JV, Ricciuti B, Ramkissoon S, Aerts JG, ...

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Calibrating observational health record data against a randomized trial

Lung cancer

Authors: Merola D, Campbell U, Lenis D, Schneeweiss S, Wang S, Madsen A, Carrigan G, Chia V, Ovbiosa OE, Pinheiro S, Pace N, Bruno A, Stewart M, Khosla S, ...

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Emulations of oncology trials using real-world data: A systematic literature review

N/A

Authors: Rider JR, Wasserman A, Slipski L, Carrigan G, Harvey R, Jiao X, McRoy L, Pace ND, Becnel L, Bruno A, Eckert JC, Hodgkins P, Jain P, Merola D, Ovbiosa ...

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Real-world treatment patterns and outcomes in patients with HR+/HER2− metastatic breast cancer treated with chemotherapy in the United States

Breast cancer

Authors: Tolaney SM, Punie K, Carey LA, Kurian AW, Ntalla I, Sjekloca N, Shah A, Rehnquist MK, Stokes M, Fraeman K, Verret W, Jhaveri K

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Treatment intensification in metastatic hormone-sensitive prostate cancer: An analysis of real-world practice patterns from the CancerLinQ Database

Prostate cancer

Authors: Eule CJ, Kuna EM, Robin TP, Gershman B, Flaig TW, Kim SP

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Addition of open administrative claims significantly improves capture of mortality in electronic health record (EHR) - focused real-world data (RWD)

Multiple tumor types

Authors: Slipski L, Dub B, Yu Y, Walker M, Natanzon Y

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Evaluation of real-world tumor response derived from electronic health record data sources: A feasibility analysis in mNSCLC patients treated with chemotherapy

Lung cancer

Authors: McKelvey BA, Garrett-Mayer E, Rivera DR, Alabaster A, Andrews HS, Bond EG, Brown TD, Bruno A, Damato L, Espirito JL, Fernandes LL, Hansen E, Kluetz ...

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Immune-related adverse events of anti-PD-(L)1 immunotherapy with and without chemotherapy in patients with advanced non-small cell lung cancer: A real-world evidence study

Lung cancer

Authors: Shao P, Archambault AN, Hampp C, Sobel RE, Asubonteng J, Geba GP, Pillai AB

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Quantification of information gained by linking claims data to an EHR cohort of US metastatic breast cancer (mBC) patients

Breast cancer

Authors: Geddes J, Katz J, Asiimwe A, Brookhart MA, Carroll C, Eldemir L, Mucaj V, Nolan K, Ntalla I, Nielson CM

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Identifying the period of heightened risk for adrenal insufficiency in patients with advanced non-small cell lung cancer treated with first-line immune checkpoint inhibitors

Lung cancer

Authors: Archambault A, Breskin A, Okoye E, Ghattas M, Byrne SE, Wang J, Asubonteng J, Hampp C

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Pediatric cancer in the United States: A comparison of two data sources

Pediatric cancers

Authors: Pace ND, Huang TH, Chen Q, Liu Y, Choi YC, McNeill A

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Representativeness of race, ethnicity and social determinants of health in patients with advanced non-small cell lung cancer via linkage of real-world electronic health records, administrative claims, and consumer financial data

Lung cancer

Authors: Calip GS, Choi YC, Cai M, Liede A, Monegro N, McNeill A

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Unlocking insights: Lesson learned from the tokenization of a psoriasis trial

Psoriasis

Authors: D'Andrea E, Choi YC, Zhang D, Tepsick J, R S, Smith H, Pinheiro S, Liede A

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A combined machine learning and natural language processing approach to determine metastatic date through integrated temporal modeling

Lung cancer

Authors: Priya V, Bhattacharyya U, Chandwani S, Ray G, Tankala S, Swaminathan K, Cohen J, Vaidya V

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A retrospective analysis of treatment patterns, overall survival, and real-world disease-free survival in early-stage non-small cell lung cancer following complete resection

Lung cancer

Authors: Hu X, Chirovsky D, Walker MS, Wang Y, Kaushiva A, Tepsick J, Samkari A

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Seeking American Society of Clinical Oncology-QualityOncology Practice Initiative (ASCO-QOPI) certification in anorthern New England rural health system and cancer care network

N/A

Authors: Perrey HM, Taylor E, Cropp BF, Bumpus MJ, Lessard S, Pretorius JA, Angus JH, Duperreault MF, Snow A, Wang D, Curtis M, Couture LA, Adolphson DR, ...

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Prognosis and conditional survival among women with newly diagnosed ovarian cancer

Ovarian cancer

Authors: Szamreta EA, Monberg MJ, Desai KD, Li Y, Othus M

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Real-world treatment patterns of adjuvant endocrine therapy and ovarian suppression in premenopausal HR+/HER2+ breast cancer

Breast cancer

Authors: Sukumar JS, Sardesai S, Ni A, Williams N, Johnson K, Quiroga D, Ramaswamy B, Wesolowski R, Cherian M, Stover DG, Gatti-Mays M, Pariser A, Sudheendra ...

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The survival benefit of adjuvant trastuzumab with or without chemotherapy in the management of small (T1mic, T1a, T1b, T1c), node negative HER2+ breast cancer

Breast cancer

Authors: Johnson KCC, Ni A, Quiroga D, Pariser AC, Sudheendra PK, Williams NO, Sardesai SD, Cherian M, Stover DG, Gatti-Mays M, Ramaswamy B, Lustberg M, ...

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EGFR mutation testing, treatment and survival in stage I–III non-small-cell lung cancer: CancerLinQ Discovery database retrospective analysis

Lung cancer

Authors: Muthusamy B, Berktas M, Li J, Thomas DS, Sun P, Taylor A, Pennell NA

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Real-world use patterns, effectiveness, and tolerability of sacituzumab govitecan for second-line and later-line treatment of metastatic triple-negative breast cancer in the United States

Breast cancer

Authors: Kalinsky K, Spring L, Yam C, Bhave MA, Ntalla I, Lai C, Sjekloca N, Stwalley B, Stokes M, Taylor A, Nanda R

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Comparing prospectively assigned trial and real-world lung cancer patients

Lung cancer

Authors: Walker B, Ray HE, Shao P, D'Ambrosio C, White C, Walker MS

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Rapid and deep prostate-specific antigen (PSA) response to apalutamide plus ADT and survival in metastatic castration-sensitive prostate cancer (mCSPC) in real world practice in the US (OASIS Project)

Prostate cancer

Authors: Maughan BL, Liu Y, Mundle S, Wang X, Karsh LI

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A real-world study on biomarker retesting among patients with non-small cell lung cancer and disparity in outcomes

Lung cancer

Authors: Crawford S, Aggarwal C, Ng S, Xu Q, Simmons A, Gulati A, Beasley MB

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Representativeness of race, ethnicity and social determinants of health in patients with advanced non-small cell lung cancer via linkage of real-world electronic health records, administrative claims, and consumer financial data

Lung cancer

Authors: Calip GS, Choi YC, Cai M, Liede A, Monegro N, McNeill A

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Real-world study on the characteristics, post-nephrectomy journey, and outcomes of patients with early-stage renal cell carcinoma based on risk groups

Renal cell carcinoma

Authors: Karam JA, Bhattacharya R, Ogbomo A, Gautam S, Yu R, Sundaram M, Imai K, Chhabra J, Haas NB

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Electronic clinical quality measure (eCQM) concordance and quality care disparities among patients with breast cancer (BC)

Breast cancer

Authors: Jones N, Lipschultz E, Blair A, Smither B, Koskimaki J, Miller RS

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Disparities in patients with HER2-positive breast cancer receiving optimal treatment: Analysis of the real-world ASCO CancerLinQ dataset

Breast cancer

Authors: Kantor O, Jones AN, Mayer EL, Chavez-MacGregor M, King TA, Mittendorf EA

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Predicting real-world overall survival for post-operative pancreatic ductal adenocarcinoma: An ASCO CancerLinQ Discovery analysis

Pancreatic cancer

Authors: Ahmed KS, Issaka SM, Marcinak CT, Zafar SN

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Real-world baseline treatment patterns and overall survival (rwOS) in patients (pts) with metastatic castration-resistant prostate cancer (mCRPC) treated with olaparib in the United States

Prostate cancer

Authors: Kariburyo-Yay F, George DJ, Aggarwal H, Tepsick JG, Yu R, Li W, Orji C, Lal LS, Ghate SR

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Dynamic machine learning model to forecast patient availability for clinical trials

Multiple myeloma

Authors: Kulkarni R, Vaidya VP, Parmar D, Tibrewal A, Parikh RB

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A prospective study comparing AI-based clinical trial eligibility screening with traditional EMR-based screening

Multiple myeloma

Authors: Joseph-Thomas J, Green C, Tibrewal A, Dupont F, Flach J, Goldstein A, Vaidya VP, Kulkarni R, Parikh RB

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Efficient site selection for clinical trials using simulated annealing

Multiple myeloma

Authors: Ruchlin I, Govil V, Samar D, Chawla J, Gurha P

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Population-based trends and outcomes for cytoreductive nephrectomy for metastatic renal cell carcinoma in the United States

Renal cell carcinoma

Authors: Wiesen B, Achua J, Warren A, Gershman B, Eule C, Kim S

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Variation in genomic testing amongst localized prostate cancer patients undergoing radical prostatectomy or radiation therapy: Results from a population-based cohort

Prostate cancer

Authors: Wiesen B, Achua J, Warren A, Konety B, Robin T, Gershman B, Flaig T, Eule C, Kim S

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Augmenting external control arms using Bayesian borrowing: a case study in first-line non-small cell lung cancer

Lung cancer

Authors: Struebing A, McKibbon C, Ruan H, Mackay E, Dennis N, Velummailum R, He P, Tanaka Y, Xiong Y, Springford A, Rosenlund M

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An emulation of the KEYNOTE-189 trial using electronic health records

Lung cancer

Authors: Merola D, Campbell U, Lenis D, Madsen A, Schneeweiss S, Wang S, Carrigan G, Taylor A, Huang J, Chia VM, Ovbiosa O, Pinheiro S, Pace ND, Bruno A, ...

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Budget impact of pirtobrutinib for patients with mantle cell lymphoma (MCL) or chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) in the United States (US)

Mantle cell lymphoma

Authors: Winfree KB, Zhang KH, Muehlenbein CE, Panjic EH, Ale-Ali A, Graham CN

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Comparative analysis of different methods of disease progression data capture in patients with metastatic castration-resistant prostate cancer

Prostate cancer

Authors: Nguyen J, Byrne C, Tang J, Patel J

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Real-world patient characteristics and treatment patterns in US patients with advanced non-small cell lung cancer

Lung cancer

Authors: Divan HA, Bittoni MA, Krishna A, Carbone DP

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Proportional randomization method to identify index line of therapy in externally controlled trials

Mantle cell lymphoma

Authors: Cui Z, Khanal M, Chen Y, Li X, Winfree K

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Integrating real-world histopathological and clinicogenomic data from 1799 lung cancer patients by applying unsupervised deep learning

Lung cancer

Authors: Wu S, Zhao Y, Luo H, Kolahi K, Bui T, Shi X, Shrotre A, Liede A, Zhao X, Samayoa J, Zhao W

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Harness the power of real-world-data for oncology target and biomarker research: A case study by applying clinic-genomics data for 2,659 lung cancer patients and beyond

Lung cancer

Authors: Wu S, Zhao W, Choi C, Cai M, Ansell P, Liede A, Chen R, Zhao X, Samayoa J

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Overall survival after treatment with first-line osimertinib for EGFR-mutant advanced NSCLC in the US

Lung cancer

Authors: Sabari JK, Yu HA, Mahadevia P, Liu Y, Demirdjian L, Sultan AA, Chen YH, Wang X, Passaro A

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KRAS co-mutational landscape dictates treatment outcomes in pancreatic cancer (PC) patients

Pancreatic cancer

Authors: Ghosh P, George R, Singh N, Agrawal S

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Identifying the genetic basis for resistance to aromatase inhibitors (AIs) in metastatic breast cancer (mBC) patients

Breast cancer

Authors: Singh N, Agrawal S

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Survival outcomes of APA as a starting treatment: Impact in real-world patients with mCSPC (OASIS)

Prostate cancer

Authors: Maughan BL, Mundle S, Nematian-Samani M, Wang X, Du S, Liu Y, Karsh LI

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Real-world homologous recombination repair mutation (HRRm) testing patterns in patients with metastatic castration-resistant prostate cancer (mCRPC) treated with olaparib in the United States

Prostate cancer

Authors: George DJ, Kariburyo-Yay F, Aggarwal H, Tepsick JG, Yu R, Li W, McLaurin KK, Orji C, Lal LS, Ghate SR

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Real-world treatment patterns, testing patterns, and clinical outcomes of first-line (1L) therapy for metastatic gastric cancer, gastroesophageal junction cancer, or esophageal adenocarcinoma (mGC/GEJC/EAC)

Gastric cancer/Gastroesophageal junction cancer

Authors: Kakehi S, Betts KA, Nie X, Kitchen SA, Ray S

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Predicting progression-free survival (PFS) in first-line (1L) immune checkpoint inhibitor (ICI)-treated patients (pts) with advanced non-small cell lung cancer (aNSCLC): Machine learning (ML) application in real-world data

Lung cancer

Authors: Hathi DK, Harnett J, Wu N, Xu Z, Pan W, Hager TG, Quek RGW, Aggarwal S, Kim Y, Rietschel P, Seebach F, Wang F, Li Y

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Identifying co-mutational signatures in STK11 mutated advanced non-small cell lung cancer (aNSCLC) patients that help overcome poor response to immune checkpoint inhibitors (ICI’s)

Lung cancer

Authors: Singh N, Agrawal S

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Characteristics, treatment patterns, and outcomes in patients with high-risk locally advanced cervical cancer

Cervical cancer

Authors: Coutinho F, Gokhale M, Doran C, Monberg M, Yamada K, Chen L

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Invasive disease-free survival as a surrogate for overall survival in patients with hormone receptor−positive/human epidermal growth factor receptor 2−negative early breast cancer: a real-world analysis

Breast cancer

Authors: Graff S, Tolaney S, Hart L, Razavi P, Janni W, Schwartzberg L, Danyliv A, Payan JCM, Ferrusi I, Adhikary RR, O'Shaughnessy J

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Real-world outcomes in metastatic HR+/HER2-, HER2+ and triple negative breast cancer after start of first-line therapy

Breast cancer

Authors: DeClue RW, Fisher MD, Gooden K, Walker MS, Le TK

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Treatment patterns and outcomes associated with sequential and non-sequential use of CDK4 & 6 inhibitors in patients with HR+, HER2− MBC in the real world

Breast cancer

Authors: Kruse M, Smyth EN, Bowman L, Gautam S, Guimaraes CM, Nisbett AR, Fisher MD, Cui ZL, Sheffield KM, Kalinsky K

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The RESECT study: Factors associated with overall survival (OS) and relapse-free survival (RFS) among patients with stages I–III resected NSCLC without known EGFR mutations

Lung cancer

Authors: Gray JE, Salomonsen R, Georgoulia N, Perez ID, Wang A, Cai L, Wetherill G, Xiao Y, Fielden C, Altorki NK

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Pitfalls with analyses of real-world data: A look at ASCO’s CancerLinQ Discovery multiple myeloma dataset

Multiple myeloma

Authors: Shou KJ, Thornton JA, Sunderland K, DeStefano C

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Uptake and efficacy of immuno-oncology combinations in metastatic renal cell carcinoma in the United States: Evidence from the ASCO CancerLinQ Discovery database

Renal cell carcinoma

Authors: Vento J, Haake SM, Beckermann K, Rini BI, Chen YW

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Implementing a BRAF biomarker electronic clinical quality measure in CancerLinQ

Colorectal cancer

Authors: Drumheller C, Barzi A, Koskimaki J

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Case studies for overcoming challenges in using big data in cancer

N/A

Authors: Sweeney SM, Hamadeh HK, Abrams N, Adam SJ, Brenner S, Connors DE, Davis GJ, Fiore LD, Gawel SH, Grossman RL, Hanlon SE, Hsu K, Kelloff GJ, Kirsch IR, ...

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Challenges to using big data in cancer

N/A

Authors: Sweeney SM, Hamadeh HK, Abrams N, Adam SJ, Brenner S, Connors DE, Davis GJ, Fiore L, Gawel SH, Grossman RL, Hanlon SE, Hsu K, Kelloff GJ, Kirsch IR, ...

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Evaluation of cost-effectiveness of adjuvant osimertinib in patients with resected EGFR mutation-positive non-small cell lung cancer

Lung cancer

Authors: Verhoek A, Cheema P, Melosky B, Samson B, Shepherd FA, de Marinis F, John T, Wu YL, Heeg B, Van Dalfsen N, Bracke B, Miranda M, Shaw S, Moldaver D

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Real-world big-data: Strengths and weaknesses of ASCO's CancerLinQ® discovery multiple myeloma dataset

Multiple myeloma

Authors: DeStefano CB, Thornton JA , Gibson SJ , Pham K, Miller RS , Sunderland K

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Health data sharing perspectives of patients receiving care in CancerLinQ-participating oncology practices

N/A

Authors: Jagsi R, Suresh K, Krenz CD, Jones RD, Griffith KA, Perry L, Hawley ST, Zikmund-Fisher B, Spector-Bagdady K, Platt J, De Vries R, Bradbury AR, Bansal ...

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Multiple myeloma in adolescent and young adults: An ASCO CancerLinQ and SEER analysis

Multiple myeloma

Authors: Gibson S, Thornton J , Sunderland K, Pham K, DeStefano C

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Prognostic impact of second primary malignancies in multiple myeloma: An ASCO CancerLinQ discovery analysis of the modern era

Multiple myeloma

Authors: Gibson SJ, Cooper JD, Pham K, Sunderland K, Thornton JA, DeStefano CB

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Real-world pitfalls of analyzing real-world data: A cautionary note and path forward

Multiple myeloma

Authors: Cooper JD, Shou K, Sunderland K, Pham K, Thornton JA, DeStefano CB

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Natural history and real-world treatment outcomes for non-small cell lung cancer patients with EGFR Exon 20 Insertion Mutation: An IASLC- ASCO CancerLinQ Study

Lung cancer

Authors: Behera M, Jiang R, Huang Z, Bunn B, Wynes MW, Switchenko J, Scagliotti GV, Belani CP, Ramalingam SS

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Real-world progression-free survival and treatment patterns for t(11;14) positive patients with multiple myeloma with at least 2 prior lines of treatment

Multiple myeloma

Authors: Girvan A, Martins D, Yu J, Ng S, Kamalakar R, Zafar F, Tulsian S, Cornell RF, Samir M

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Real-world treatment patterns and healthcare resource utilization in patients with Waldenström macroglobulinemia initiating first-line treatment with ibrutinib or zanubrutinib

Waldenström macroglobulinemia

Authors: Paludo J, Sarosiek SR, von Keudell GR, Salkar M, Zhou S, Kim S, Cheng N, Pacia M, Karve S, Castillo JJ

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Real-world analysis of a large electronic medical record database of patients with higher-risk myelodysplastic neoplasms (HR MDS): Treatment profiles, clinical effectiveness, and key adverse event rates

Myelodysplastic syndrome

Authors: Shah R, Thanataveerat A, Rudraraju R, Curtis K, Jhaveri TZ, Askin G, Irwin DE, Pierzynski J, Hogea C, Sabate EJ, Sali AP, Williamson M

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Real-world outcomes with adjuvant nonsteroidal aromatase inhibitors (NSAIs) vs tamoxifen (TAM) in patients with hormone receptor−positive/human epidermal growth factor receptor 2−negative (HR+/HER2−) early breast cancer (EBC): A US database analysis

Breast cancer

Authors: Graff SL, Tolaney SM, Hart LL, Razavi P, Fasching PA, Janni W, Schwartzberg LS, Lanoue B, Salas TR, Khakwani A, McDermott C, Pathak P, O'Shaughnessy J

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Real-world outcomes of different lines and sequences of treatment in BRAF-positive advanced melanoma patients

Melanoma

Authors: Betof Warner A, Tarhini A, Kang B, Nakasato A, Ling YL, Shah R, Tang J, Patel J

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Adverse events and clinical outcomes in patients treated with PD-(L)1 blockade for advanced non-small-cell lung cancer

Lung cancer

Authors: Zhang Y, Doran C, Le TK, Dreyfus B, Kola N, Sylvester BE, Lal L, Penrod JR, Meadows Shropshire S

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clinical characteristics and outcomes of Black patients with multiple myeloma compared with other races

Multiple myeloma

Authors: Spence S, Yu J, Girvan A, Ng S, Li S, Zafar F, Yellow-Duke A, Cornell RF

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Post-metastasis survival in high-risk localised and locally advanced prostate cancer patients undergoing primary treatment in the United States: A retrospective study

Prostate cancer

Authors: Freedland S, Fernandes L, De Solda F, Buyukkaramikli N, Mundle SD, McCarthy SA, Labson D, Yang L, Pan F, Mir C

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Clinical and economic impact of recurrence in early-stage non-small-cell lung cancer following complete resection

Lung cancer

Authors: West H, Hu X, Chirovsky D, Walker MS, Wang Y, Kaushiva A, Tepsick J, Samkari A

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Real-world treatment patterns and outcomes of patients with metastatic nonsquamous non-small cell lung cancer after progression on standard-of-care therapy in the United States

Lung cancer

Authors: Divan HA , Bittoni MA, Krishna A, Carbone DP

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Impact of ibrutinib dose reduction on duration of therapy in patients with chronic lymphocytic leukemia/small lymphocytic lymphoma

Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

Authors: Shadman M, Karve S, Patel S, Rava A, Sun H, Howarth A, Tomicki S, Srivastava BP, Stephens DM

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Machine learning (ML) on real-world data (RWD) of front-line (1L) metastatic castration resistance prostate cancer (mCRPC) patients for dynamic prediction of time to tx discontinuation (TTD)

Prostate cancer

Authors: Jain P, Hathi DK, Honarvar H, Das RK

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Mortality among EGFR-mutated advanced NSCLC patients after frontline osimertinib treatment: A real-world, US attrition analysis

Lung cancer

Authors: Girard N, Leighl N, Ohe Y, Kim TM, Demirdjian L, Bourla AB, Sultan AA, Mahadevia P, Bauml JM, Sabari J

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Augmentation of real-world mortality data in the electronic medical record: Assessing the impact on overall survival estimates in multiple myeloma

Multiple myeloma

Authors: Liu P, Lan Z, Walker B, Ray HE, Smith H

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LUMINATE-103: Real-world treatment patterns and outcomes of patients (pts) with epidermal growth factor receptor mutant (EGFR MU), non-squamous (NSQ) locally advanced/metastatic non-small cell lung cancer (a/mNSCLC): Pooled analysis of large US electronic health record (EHR) datasets

Lung cancer

Authors: Cho BC, Xu Q, Ng S, Goldman JW, Girard N, Planchard D, Baijal S, Kamalakar R, Blot V, Alhasani H, Karve S, Lu S

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Site of metastasis (SoM) and its impact on clinical outcomes in 8 cancer cohorts

Multiple tumor types

Authors: George R, Singh N, Vidal L, Hajek E, Skalska D, Saini KS, Agrawal S

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Development of natural language processing (NLP) models for extracting key features from unstructured notes to create real-world data (RWD) assets for clinical research at scale

Lung cancer

Authors: Agrawal S, George R, Vaidya VP, Chakkrapani S, Prajapati R, Tankala S, Parmar D, Lakkimsetty VPS, Bhardwaj T, Ashwani A, Mendonca E, Narayanan B, ...

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Enhancement in line of therapy (LoT) derivation from real-world data (RWD) from electronic health records (EHR) via integration of medical claims data

N/A

Authors: Agrawal S, B AP, George R, Singh N, Soni M, Chakkrapani S, Priya V, Vaidya VP

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An adjusted treatment comparison comparing amivantamab versus real-world clinical practice in Europe and the United States for patients with advanced non-small cell lung cancer with activating epidermal growth factor receptor exon 20 insertion mutations

Lung cancer

Authors: Chouaid C, Bosquet L, Girard N, Kron A, Scheffler M, Griesinger F, Sebastian M, Trigo J, Viteri S, Knott C, Rodrigues B, Rahhali N, Cabrieto J, Diels ...

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Comparative effectiveness of abiraterone and enzalutamide in the first-line treatment of metastatic castration-resistant prostate cancer (mCRPC): A retrospective cohort study in a large database of deeply curated EHR real-world data (RWD) from community oncology practices in the US

Prostate cancer

Authors: An H, Schoen MW, Rider J, Schorer AE, Ken J, Chen L, Alabaster A, Natanzon Y

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Improving real-world mortality data quality in oncology research: Augmenting electronic medical records with obituary, Social Security Death Index, and commercial claims data

Melanoma

Authors: Shao P, Tepsick JG, Walker B, Ray HE

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Machine learning (ML) model for prediction of pneumonitis using real-world data (RWD) on immune checkpoint inhibitor (ICI)-treated advanced non-small cell lung cancer (aNSCLC)

Lung cancer

Authors: Hall H, Mueller J, Cai MH, Liu Y, Liede A, Das R, Hathi D

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Real-world evaluation of outcomes in relapsed/refractory multiple myeloma patients that are triple-class exposed after receiving 2 or more prior lines of therapy

Multiple myeloma

Authors: Radwanski K, Yu J, Pierce K, Talati C, Stricker S, Jiao S, Bueno O

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Machine learning approach to understand real-world treatment in patients with higher-risk myelodysplastic syndromes

Myelodysplastic syndrome

Authors: Priya V, Vaidya VP, Agrawal S, Singh N, Chatra K, Parmar D, Yan R, Das RK, Haririfar M, McMahon P, Williamson M, Sadek I, Hogea C

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Impact of real-world treatment sequencing patterns on time to next treatment among patients with chronic lymphocytic leukemia in the United States

Chronic Lymphocytic Leukemia

Authors: Chanan-Khan AA, Challagulla S, Kaushiva A, Miller V, Wang Y, Smith H, Yang K

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Racial and ethnic representation in large B-cell lymphoma trials and real-world databases

Large B-Cell Lymphoma

Authors: Munoz J, Mutebi A, Wang T, Zhang G, Yu J, He J, Chibber A, Kamalakar R, Jun MP, Adejumo K, Yang S, Kalsekar A

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Machine learning (ML) model for prediction of pneumonitis using real-world data (RWD) on immune checkpoint inhibitor (ICI)-treated advanced non-small cell lung cancer (aNSCLC)

Lung cancer

Authors: Hathi DK, Hall H, Mueller J, Cai MH, Liu Y, Liede A, Das RK

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Real-world outcomes among patients with metastatic colorectal cancer treated first line with a bevacizumab biosimilar (bevacizumab-awwb)

Colorectal cancer

Authors: Jin R, Ogbomo AS, Accortt NA, Lal LS, Bishi G, Sandschafer D, Goldschmidt JH

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Real-world (RW) use patterns, effectiveness, and tolerability of sacituzumab govitecan (SG) for second-line (2L) and later treatment of metastatic triple-negative breast cancer (mTNBC)

Breast cancer

Authors: Kalinsky K, Spring L, Yam C, Taylor A, Sjekloca N, Kaushiva A, Lai C, Ntalla I, Nanda R

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Picturing progression: A new role of whole slide imaging in comprehensive clinical genomic datasets

Lung cancer, colorectal cancer

Authors: Sweeney EG, Wang YJ, Picard J, Abraham J, Amidi E, Rossi MR, Klimov S, D'Ambrosio C, Chen M, Elton J, Sledge G

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Genomic landscape of patients with non-small cell lung cancer (NSCLC)

Lung cancer

Authors: Singh NK, Saini KS, Chakkrapani S, Severson E, Nagaraj N, Ramkissoon S, Chico I, Aguilo A, George R, Vidal L, Agrawal S

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Real-world treatment (Tx) patterns in patients (pts) with HR+/HER2- metastatic breast cancer (mBC) treated with chemotherapy (CT) in the United States (US)

Breast cancer

Authors: Punie K, Jhaveri , Tolaney SM, Ntalla I, Shah A, Sjekloca N, Fraeman K, Carey LA

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Real-world analysis of a large electronic medical record database of patients with higher-risk myelodysplastic syndromes (HR MDS): Treatment profiles, clinical effectiveness, and key adverse events

Myelodysplastic syndrome

Authors: Shah R, Thanataveerat A, Rudraraju R, Curtis K, Jhaveri TZ, Askin G, Irwin D, Dinoso J, Hogea C, Sabate EJ, Radford M, Sali AP, Williamson M

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Real-world clinical outcomes in patients (pts) with HR+/HER2- metastatic breast cancer (mBC) treated with chemotherapy (CT) in the United States (US)

Breast cancer

Authors: Tolaney SM, Punie K, Kurian AW, Ntalla I, Verret W, Sadetsky N, Sjekloca N, Stokes M, Jhaveri KL

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Real-world outcomes in patients (pts) with metastatic triple-negative breast cancer (mTNBC) treated with sacituzumab govitecan (SG) in 2L+ in the United States (US)

Breast cancer

Authors: Kalinsky K, Spring L, Yam C, Taylor A, Sjekloca N, Kaushiva A, Lai C, Ntalla I, Nanda R

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Real-world management and outcomes for newly diagnosed AML patients initiating Venetoclax and hypomethylating agents in US community practice

Acute Myeloid Leukemia

Authors: Wang Y, McNeill AM, Doran C, Cain LE, Liu Y, Lan Y, Cheng WH, Pullarkat V

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A real-world study of US patients with metastatic ovarian, fallopian tube, and peritoneal cancer (mOFPC) using integrated electronic health records (EHR) and claims datasets

Ovarian cancer

Authors: B AP, Funingana G, Singh N, George R, Sowa A, Chakkrapani S, Priya V, Vaidya VP, Vidal L, Saini KS, Agrawal S

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Association between severe adverse event management and overall survival in patients treated with immune checkpoint inhibitor with advanced non–small-cell lung cancer

Lung cancer

Authors: Naidoo J, Johnson DB, Doran C, Wang Y, Zhang Y, Le TK, Hopson S, Dreyfus B, Lal LS, Vyas C, Goldstein S, Izadi Z

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Unfavorable early-stage Hodgkin lymphoma: assessment of patient characteristics in a real-world setting

Classical Hodgkin’s lymphoma

Authors: Gautam S, Yeola S, Nahar A, Sarpong EM, Prescott J, Yang X, Sineshaw HM

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Patient profiles, treatment patterns, and outcomes among persistent, recurrent, or metastatic cervical cancer patients under routine care in the United States

Cervical cancer

Authors: Gokhale M, Yu R, Monberg M, Tekin C, Chen L, DeClue RW, Knapp K, Lal LS

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Treatment patterns and outcomes among locally advanced cervical cancer patients receiving concurrent chemoradiotherapy

Cervical cancer

Authors: Coutinho F, Gokhale M, Doran C, Monberg M, Yamada KS, Chen L

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Real-world response endpoints in patients with mNSCLC treated with chemotherapy across real-world datasets

Lung cancer

Authors: McKelvey BA, Garrett-Mayer E, Belli AJ, Brown TD, Dow J, Espirito JL, Kluetz P, Ma X, McCracken A, Mishra-Kalyani PS, Natanzon Y, Potter D, Rivera D, ...

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Comparison of advanced ovarian cancer patients treated with or without bevacizumab in the US community oncology clinics

Ovarian cancer

Authors: DeClue RW, Szamreta EA, Gautam S, Fisher MD, Monberg MJ

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Real-world management and outcomes for newly diagnosed AML patients initiating Venetoclax and hypomethylating agents in US community practice

Acute Myeloid Leukemia

Authors: McNeill AM, Wang Y, Doran C, Cain LE, Liu Y, Lan Z, Pullarkat V

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Treatment outcomes in patients (pts) with advanced/metastatic non‑small cell lung cancer (NSCLC) harboring MET amplification as a secondary oncogenic driver

Lung cancer

Authors: Ryder A, Oksen D, Boutmy E, Ellers-Lenz B, Stroh C, Karachaliou N

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Biomarker testing and treatment patterns in US patients (pts) with advanced/metastatic non‑small cell lung cancer (NSCLC) harboring MET amplification

Lung cancer

Authors: Ryder A, Oksen D, Boutmy E, Wang Y, Nisbett AR, Stroh C, Johne A

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Real-World Effectiveness and Treatment Patterns of Venetoclax-Based Regimens Among Patients with Chronic Lymphocytic Leukemia (CLL) Treated in Community Settings

Chronic Lymphocytic Leukemia

Authors: Zakeri M, Emechebe N, Chowdhery R, Jawaid D, Alhasani H, Manzoor BS

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Real-world study on characteristics, post-nephrectomy journey, and outcomes of patients with early-stage renal cell carcinoma based on risk groups

Renal cell carcinoma

Authors: Karam JA, Bhattacharya R, Ogbomo A, Gautam S, Yu R, Sundaram M, Imai K, Chhabra J, Haas NB

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Evaluating clinical trial inclusion/exclusion criteria from claims using generative artificial intelligence

N/A

Authors: Mueller J, Parikh RB, Noble A

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Electronic health record (EHR) and genomics-based machine learning (ML) to predict therapeutic effectiveness among patients with hormone-receptor positive (HR)+/HER2- advanced breast cancer (aBC)

Breast cancer

Authors: Hathi DK, Pisano S, Honarvar H, Parikh RB, Das RK

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Risk of Death Before and After Metastasis in High-Risk Localized and Locally Advanced Prostate Cancer Patients Undergoing Radical Prostatectomy or Radiotherapy as Primary Treatment in the United States: A Retrospective Study

Prostate cancer

Authors: Freedland S, Fernandes L, De Solda F, Buyukkaramikli N, Labson D, Yang L, Pan F, Mir MC

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Assessment of electronic health record (EHR) –based machine learning (ML) in predicting risk of brain metastasis among patients with early-stage non–small-cell lung cancer (eNSCLC)

Lung cancer

Authors: Honarvar H, Hathi DK, Parikh RB, Das RK

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Identification of biomarkers for early progression in muscle invasive bladder cancer (MIBC) using real-world data

Bladder cancer

Authors: Singh N, George R, Agrawal S

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Digital trial solutions eScreening: software to rank patients by their predicted clinical trial eligibility using real-world data and machine learning

N/A

Authors: Bhandari S, Levonian Z, Annand R, Baxter J-Z, Cain J, Flach J, Joseph-Thomas J, Mueller J

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A machine learning model to facilitate patient-level risk screening in myelodysplastic syndromes (MDS) patients in routine clinical practice

Myelodysplastic syndrome

Authors: Vaidya V, Vaidya V, Priya V, Parmar D, Yan R, Das R, Haririfar M, McMahon P, Williamson M, Hogea C

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Electronic health record (EHR)-based machine learning (ML) to predict disease recurrence after surgical resection of early-stage non-small cell lung cancer (eNSCLC)

Lung cancer

Authors: Pisano S, Honarvar H, Parikh RB, Das RK

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Real-world treatment patterns and clinical outcomes post standard of care (SOC) among patients (pts) with metastatic non-small cell lung cancer (mNSCLC) with and without actionable genomic alterations (AGAs) in the United States (US)

Lung cancer

Authors: Shah R, Kariburyo-Yay F, Apple J, Lal LS, Miller V, Kwong J, Reuss JE

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LUMINATE 102: A real-world study on biomarker testing rates among patients with non-small cell lung cancer (NSCLC) across lines of therapy

Lung cancer

Authors: Aggarwal C, Xu Q, Ng S, Kamalakar R, Crawford S, Beruti S, Myftiu A, Beasley MB

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Real-world rebiopsy and biomarker retesting rates among patients with non-small cell lung cancer across patient demographics in the United States

Lung cancer

Authors: Aggarwal C, Xu Q, Ng S, Kamalakar R, Crawford S, Beruti S, Myftiu A, Beasley MB

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Real-world outcomes in patients with EGFR wildtype non-squamous locally advanced/metastatic NSCLC receiving second- or third-line docetaxel: Pooled analysis from LUMINATE-101

Lung cancer

Authors: Girard N, Xu Q, Camidge DR, Baijal S, Karve S, Ng S, Kamalakar R, Ratajczak C, Allen A, Lu S

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Augmenting synthetic control arms using Bayesian borrowing: a case study in first-line non-small cell lung cancer

Lung cancer

Authors: Strübing A, McKibbon C, Ruan H, Mackay E, Dennis N, Velummailum R, He P, Tanaka Y, Xiong Y, Springford A, Rosenlund M

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Evaluation of treatment strategies for patients with stage IIIA non-small cell lung cancer in the immunotherapy era

Lung cancer

Authors: Alabaster A, Velotta JB, Tupper HI, Natanzon Y

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Real-world treatment patterns and sequencing in patients with locally advanced or metastatic urothelial cancer (la/mUC) in the US

Bladder cancer

Authors: Kearney M, Mahmoudpour H, Ike C, Modh A, Monzon S, Fragkogianni M, Carson K

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Disparities in genetic testing patterns and positivity among patients with breast cancer in the CancerLINQ real-world oncology database

Breast cancer

Authors: Kantor O, Jones A, Bychkovsky B, Laws A, Weiss A, Rana H, Garber J, Scheib R, Chavez M, Mayer E, King T, Mittendorf E

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Patient characteristics, treatment patterns, and factors of biomarker testing among patients with advanced non-small cell lung cancer (ANSCLC) in the US, 2012-2020

Lung cancer

Authors: Yang M, MacEwan J, Honnold R, McClain MR, O'Hara R, Liu F, Paik P

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Association of clinical trial enrollment and mortality amongst patients with advanced prostate cancer

Prostate cancer

Authors: Pessoa RR, Flaig T, Robin T, Gershman B, Bronsert M, Kiani K, Ballon-Landa E, Eule C, Kessler E, Smaldone MC, Kim SP

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Variation of hormonal agent usage with postoperative radiation therapy: Results from a population based cohort of prostate cancer patients in community oncology practices

Prostate cancer

Authors: Pessoa RR, Robin T, Flaig T, Molina E, Gershman B, Ballon-Landa E, Eule C, Kessler E, Chapin B, Smaldone MC, Kim SP

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Chasm between cancer quality measures and electronic health record data quality

N/A

Authors: Schorer AE, Moldwin R, Koskimaki J, Bernstam EV, Venepalli NK, Miller RS, Chen JL

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Quantitating and assessing interoperability between electronic health records

N/A

Authors: Bernstam EV, Warner JL, Krauss JC, Ambinder E, Rubinstein WS, Komatsoulis G, Miller RS, Chen JL

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Retrospective analysis of real-world management of EGFR-mutated advanced NSCLC, after first-line EGFR-TKI treatment: US treatment patterns, attrition, and survival data

Lung cancer

Authors: Nieva J, Reckamp KL, Potter D, Taylor A, Sun P

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Incidence of Severe Acute Respiratory Syndrome Coronavirus 2 and Subsequent Mortality in a Multisite Cohort of Patients With Cancer in the CancerLinQ Discovery Database

Multiple tumor types

Authors: Ray EM, Riffon MF, Kakamada S, Miller RS, Potter D

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Cancer registry data linkage of electronic health record data from ASCO's CancerLinQ: Evaluation of advantages, limitations, and lessons learned

N/A

Authors: Charlton ME, Kahl AR, McDowell BD, Miller RS, Komatsoulis G, Koskimaki JE, Rivera DR, Cronin KA

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Survival in the real world: A national analysis of patients treated for early-stage breast cancer

Breast cancer

Authors: Gidwani R, Franks JA, Enogela EM, Caston NE, Williams CP, Aswani MS, Azuero A, Rocque GB

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Reaching beyond maximum grade: progress and future directions for modernising the assessment and reporting of adverse events in haematological malignancies

Hematological malignancies

Authors: Thanarajasingam G, Minasian LM, Bhatnagar V, Cavalli F, De Claro RA, Dueck AC, El-Galaly TC, Everest N, Geissler J, Gisselbrecht C, Gormley N, ...

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Real-world clinical outcomes of patients with BRCA-mutated, human epidermal growth factor receptor 2 (HER2)-negative metastatic breast cancer: a CancerLinQ® study

Breast cancer

Authors: Miller RS, Mokiou S, Taylor A, Sun P, Baria K

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Racial differences in patient-reported symptoms and adherence to adjuvant endocrine therapy among women with early-stage, hormone receptor-positive breast cancer

Breast cancer

Authors: Hu X, Walker MS, Stepanski E, Kaplan CM, Martin MY, Vidal GA, Schwartzberg LS, Graetz I

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Efficacy of lurbinectedin in a clinical trial versus standard of care in a real-world comparator arm in relapsed/refractory small cell lung cancer patients

Lung cancer

Authors: Ganti AK, Prince P, Wang X, Estrin A, Boccuti A, Rengarajan B, Naveh N, D'Agostino Jr. R, Alvord T, Ben-Joseph R

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Machine learning modeling of real-world primary resistance and hyperprogression in immune checkpoint inhibitor (ICI) treated advanced non-small cell lung cancer (aNSCLC) patients

Lung cancer

Authors: Das RK, Hathi DK

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Disparities in timely treatment among lung cancer patients

Lung cancer

Authors: Chhabra J, Ray H, Derkach S, Thompson D, Whyte W

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Amivantamab compared with real-world therapies in patients with advanced non-small cell lung cancer harboring EGFR exon 20 insertion mutations who progressed after platinum-based chemotherapy

Lung cancer

Authors: Minchom A, Viteri S, Bazhenova L, Gadgeel SM, Ou SHI, Trigo J, Bauml JM, Backenroth D, Bhattacharya A, Li T, Mahadevia P, Girard N

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Real-world treatment patterns and outcomes of daratumumab retreatment in multiple myeloma in the United States

Multiple myeloma

Authors: Girvan A, Yu J, Emechebe N, Kamalakar R, Luo Y

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Treatment patterns and outcomes in patients with relapsed/refractory multiple myeloma receiving ≥3 lines of therapy: A real-world evaluation in the United States

Multiple myeloma

Authors: Girvan A, Yu J, Kamalakar R, Mearns ES, Nixon M, Cornell RF

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Real-world outcomes among patients with metastatic colorectal cancer treated first line with bevacizumab-awwb

Colorectal cancer

Authors: Jin R, Ogbomo AS, Accortt NA, Lal LS, Bishi G, Sandschafer D, Goldschmidt JH

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STREAMLINE - Retrospective cohort study of FLT3-mutated acute myeloid leukemia (AML): Real-world treatment patterns and clinical outcomes after first relapse or refractory (R/R) diagnosis

Acute Myeloid Leukemia

Authors: Zeidan AM, Gautam S, Yu R, Lan Z, Grinblatt DL, ElSouda D, Spalding J, Block A, Touya M, Pandya BJ

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Natural language processing-optimized case selection for real-world evidence studies

Lung cancer

Authors: Koskimaki J, Hu J, Zhang Y, Mena J, Jones N, Lipschultz E, Vaidya VP, Altay G, Erese VA, Swaminathan KK, Mendonca E, Dutt T, Singh K, King T, ...

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Real-world outcomes among HER2-positive metastatic breast cancer patients treated with trastuzumab deruxtecan in the United States

Breast cancer

Authors: Kariburyo-Yay F, Mehta S, Kwong J, Lam C, Doran C, Lan Z

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Unmet need in heavily pre-treated patients with HR+/HER2- metastatic breast cancer (mBC) in the US: a ConcertAI analysis

Breast cancer

Authors: Waks AG, Gharaibeh M, Sjekloca N, Poluparthi N, Shah A, Bergamaco E, MacCannell T, Leung G, Ntalla I, Oko-osi H, Tolaney SM

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Use of immunosuppressive drugs and the effectiveness of immune checkpoint inhibitor therapy among patients with advanced/metastatic non-small cell lung cancer in the United States

Lung cancer

Authors: Dreyfus B, Zhang E, Doran C, Le K, Kola C, Sylvester BE, Punekar R, Lal L, Penrod J, Meadows-Shropshire SL

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Outcomes among patients with mantle cell lymphoma post-covalent BTK inhibitor therapy in the United States: a real-world electronic medical records study

Mantle cell lymphoma

Authors: Hess LM, Chen Y, Abada PB, Konig H, Walgren RA

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Outcomes for patients with mantle cell lymphoma post-covalent BTK inhibitor therapy in the United States and Japan: a study of two real-world databases

Mantle cell lymphoma

Authors: Rai S, Hess LM, Chen Y, Bowman L, Abada PB, Konig H, Walgren RA, Tanizawa Y, Cai Z, Tajimi M

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Outcomes for patients with chronic lymphocytic leukemia (CLL) previously treated with both a covalent BTK and BCL2 inhibitor in the United States: A real-world database study

Chronic Lymphocytic Leukemia

Authors: Mato AR, Hess LM, Chen Y, Abada PB, Konig H, Pagel JM, Walgren RA

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Real-world patient profiles, treatment patterns, and outcomes among recurrent, persistent, and metastatic cervical cancer patients

Cervical cancer

Authors: Gokhale M, Yu R, Monberg M, Tekin C, Fan L, DeClue R, Knapp K, Lal LS

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Early-stage unfavorable Hodgkin lymphoma: Patient characteristics in real-world oncology data from the United States

Classical Hodgkin’s lymphoma

Authors: Gautam S, Yeola S, Nahar A, Sarpong EM, Prescott J, Yang X, Sineshaw HM

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Treatment patterns and clinical outcomes among patients with relapsed/refractory classical Hodgkin's lymphoma

Classical Hodgkin’s lymphoma

Authors: Nisbett AR, Yang X, Squires P, Gautam S, Desai K, Raut M, Nahar A

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Disease-free and overall survival outcomes for localized RCC patients by disease stage

Renal cell carcinoma

Authors: Haas NB, Bhattacharya R, Ogbomo AS, Imai K, Gautam S, Rogerio J, Yu R, Chhabra J, Sundaram M

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Treatment patterns and outcomes among patients with EGFR-mutant advanced NSCLC in the frontline and post-osimertinib settings

Lung cancer

Authors: Sabari J, Pisano S, Gemmler K, Mueller J, Bernabé Caro R, Girard N, Goto K, Leighl N, Ohe Y, Kim TM, Lee S-H, Demirdjian L, Rudolph S, Mahadevia P, ...

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Lurbinectedin vs an external control arm in patients with small cell lung cancer

Lung cancer

Authors: Ganti AK, Prince P, Wang X, Estrin A, Boccuti A, Rengarajan B, Naveh N, D'Agostino Jr. R, Alvord T, Ben-Joseph R

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Disease-free survival (DFS) as a predictor of overall survival in completely reseacted early-stage non-small cell lung cancer (NSCLC)

Lung cancer

Authors: West H, Hu X, Burke T, Walker MS, Wang Y, Samkari A

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Treatment patterns, overall survival (OS), and disease-free survival (DFS) in early-stage non-small cell lung cancer (NSCLC) following complete resection

Lung cancer

Authors: West H, Hu X, Burke T, Walker MS, Wang Y, Samkari A

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Racial disparities in newly diagnosed hematological malignancies in the United States during the COVID-19 pandemic, January 2020 to March 2021

Hematological malignancies

Authors: Bhandari S, Chawla J, Jain P, Kaushiva A, Lagor C, Lal L, Mueller J, Whyte W

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Identifying genetic factors of response and resistance to CDK4/6 inhibitors in metastatic HR+/HER2-breast cancer using real-world data

Breast cancer

Authors: Agrawal S, Singh N, Narayanan B

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Impact of trial site selection on minority patient recruitment in prostate cancer trials

Prostate cancer

Authors: Lagor C, Bhandari S, Chawla J, Knight M, Mann J, Mueller J, Raska P, Southwick S, Whyte W

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Effect of COVID-19 vaccination status on adverse events and outcomes in advanced non-small cell lung cancer (aNSCLC) patients treated with immunotherapies

Lung cancer

Authors: George R, Narayanan B, Agrawal S

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Evaluating the impact of performance status criteria on minority eligibility for oncology clinical trials

N/A

Authors: Bhandari S, Mann J, Chawla J, Jain P, Knight M, Lagor C, Mueller J, Raska P, Southwick S, Whyte W

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Comparison of DNA sequencing, immunohistochemistry, and in-situ hybridization techniques to determine HER2 status in metastatic breast cancer patients

Breast cancer

Authors: Lal LS, Milne D, Walker MS, Kovach M

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Cohort optimizer, a software solution that uses real-world data and AI to optimize criteria of oncology trials

N/A

Authors: Bhandari S, Mann J, Hajela R, Govil V, Greatti Y, Maguire R, Powers J, Southwick S, Mueller J

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Clinical outcomes with alpelisib (ALP) plus fulvestrant (FUL) after prior treatment (tx) with FUL in patients (pts) with advanced breast cancer (ABC): A real-world (RW) analysis

Breast cancer

Authors: O'Shaughnessy J, Woeckel A, Pistilli B, Hegg R, Vahdat LT, Vuina D, Zadeh PA, Smith TW, Kim J, Krop I

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Identifying genetic factors for resistance and response to immune checkpoint inhibitors (ICIS) in advanced non-small cell lung cancer (aNSCLC) patients using real-world data

Lung cancer

Authors: Singh NK, Agrawal S, Narayanan B

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Race differences in patient-reported symptoms and adherence to adjuvant endocrine therapy among women with early-stage, hormone receptor-positive breast cancer

Breast cancer

Authors: Hu X, Walker MS, Stepanski E, Kaplan C, Martin MY, Vidal GA, Schwartzberg LS, Graetz I

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Treatment effectiveness in a rare oncology indication: Lessons from an external control cohort study

Lung cancer

Authors: Oksen D, Prince P, Boutmy E, Garry EM, Ellers-Lenz B, Estrin A, Johne A, Verpillat P, Gatto NM

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Associations between biomarker testing and characteristics of patients with metastatic non–small cell lung cancer (mNSCLC): An analysis of CancerLinQ Discovery (CLQD) data

Lung cancer

Authors: Mileham KF, Garrett-Mayer E, Kaltenbaugh M, Kirkwood MK, Schenkel C, Bruinooge SS, Osarogiagbon RU, Jalal SI, Moore A, Roy UKB, Freeman-Daily J, ...

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Molecular testing and patterns of treatment in NSCLC patients: An IASLC analysis of ASCO CancerLinQ Discovery data

Lung cancer

Authors: Behera M, Joseph G, Rupji M, Huang Z, Bunn B, Wynes M, Switchenko JM, Scagliotti GV, Higgins KA, Tsao MS, Belani CP, Sequist LV, Ramalingam SS

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The survival benefit of anti-HER2 treatment in the management of small (T1mic, T1a, T1b, T1c), node-negative HER2+ breast cancer

Breast cancer

Authors: Johnson KCC, Ni A, Grimm M, Sardesai SD, Stover DG, Cherian MA, Gatti-Mays ME, Pariser A, Sudheendra PK, Williams NO, VanDeusen JB, Ramaswamy B, ...

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Diagnosed with advanced prostate cancer: A population-based cohort from national oncology practices

Prostate cancer

Authors: Kim SP, Kiani K, Konety B, Bronsert M, Candelario N, Kessler ER, Gershman B, Tyler R, Flaig TW

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Characterizing node-negative non-small cell lung cancer patients with similarity networks: A CancerLinQ Discovery analysis

Lung cancer

Authors: Moen EL, Chen Z, Schaefer A, Bhimani A, O'Malley J, Dragnev KH

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Long term survival outcomes in NSCLC patients with targeted therapy and immunotherapy: An IASLC analysis of ASCO CancerLinQ Discovery data

Lung cancer

Authors: Behera M, Joseph G, Rupji M, Huang Z, Bunn B, Wynes M, Switchenko J, Scagliotti G, Higgins K, Tsao M, Belani C, Sequist L, Ramalingam SS

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Demographics, clinical characteristics, treatment patterns and clinical outcomes of patients with stages I-III resected NSCLC without known EGFR mutations

Lung cancer

Authors: Altorki NK, Salmonsen R, Georgoulia NE, Perez ID, Wang A, Cai L, Wetherill G, Xiao Y, Fielden C, Gray JE

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Real world treatment patterns of adjuvant endocrine therapy and ovarian suppression in premenopausal HR+/HER2+ breast cancer

Breast cancer

Authors: Sukumar JS, Sardesai S, Ni A, Williams N, Ramaswamy B, Wesolowski R, Cherian MA, Stover D, Gatti-Mays M, Pariser AC, Sudheendra PK, George MA, ...

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Secondary primary malignancies (SPMs) in adolescent and young adults (AYAs) with multiple myeloma (MM): An ASCO CancerLinQ analysis

Multiple myeloma

Authors: Gibson SJ, Cooper JD, Thornton JA, Pham K, Sunderland K, DeStefano CB

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Survival of patients with multiple myeloma diagnosed with second primary malignancies: An ASCO CancerLinQ analysis

Multiple myeloma

Authors: Cooper JD, Thornton JA, Gibson SJ, Pham K, Sunderland K, DeStefano CB

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